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- Autor:
- Eduardo Anitua
- Gorka Orive
- Sabino Padilla
- Mar Zalduendo
- María Troya
Leukocyte inclusion within a platelet rich plasma-derived fibrin scaffold stimulates a more pro-inflammatory environment and alters fibrin properties
PLoS One. 2015 Mar 30;10(3):e0121713. One of the main differences among platelet-rich plasma (PRP) products is the inclusion of leukocytes that may affect the biological efficacy of these autologous preparations. The purpose of this study was to evaluate whether the addition of leukocytes modified the morphological, biomechanical and biological properties of PRP under normal and inflammatory conditions.